Shampoo Pedilin: contraindications, instructions for use, analogues, reviews

Shampoo Pedilin: contraindications, instructions for use, analogues, reviews

Antiparasitic Shampoo Pedilin — the international name Pedilin, is prescribed for the treatment of pediculosis caused by Pediculus humanus capitis. Producer of shampoo Pedilin — Slovenia, Krka. More details about instructions for use, reviews, price and analogues of Pedilin from lice will tell you in this educational material.

Features of the drug

Shampoo Pedilin is an antiparasitic drug for the treatment of pediculosis — infection of the scalp with lice.


  • The shampoo Pedilin contains:
    • as the active ingredient — malathion;
    • as auxiliary substances — propylene glycol, alkyl sulfate, sodium lauryl ethyl sulfate, dyes, flavors, water.
  • The emulsion contains tetramethrin, piperonyl butoxide.

On how much it costs pedigree shampoo, read below.

Dosage forms

  • shampoo,
  • gel,
  • emulsion Pedilin, the price of the 100 ml bottle is 290 rubles on average.

Pharmacological action Pedilin

Pedilin is a combined preparation that includes insecticides:

  • malathion;
  • tetramethrin.

The medication action of Pedilin is the result of the combined action of its constituent components.


Malathion( carbofos) is an organophosphorous antiparasitic agent that can easily penetrate the body of an insect through the chitinous cover. In the body of a parasitic insect, the action of the enzyme acetylcholinesterase is blocked. In the insect’s body, malathion is oxidized, turning into a malaoxon — an even more toxic substance than malathion.

This reaction is not inherent in plants and warm-blooded organisms, which is the reason for the high toxicity of malathion for insects and makes it less dangerous for humans and animals. Poisoning of an insect occurs as a result of poisoning with accumulated acetylcholine.

Under the influence of malathion, lice, nits, and scabies are killed. Tetrametrine is a synthetic insecticide from the pyrethrin group. The poisoning effect of tetrametrin has on the nervous system of an insect, causing convulsions and paralysis.


Malathionine can penetrate the body through the lungs, skin, mucous membranes, but can not accumulate.


The drug is intended for the treatment of pediculosis of the scalp of adults and children, as well as the baby. Allowed during pregnancy and lactation.

Instruction for use

For one treatment of the scalp requires 10 to 60 ml of Pedilin shampoo depending on the length and thickness of the hair. Using a cotton swab, the shampoo is evenly distributed over wet hair and scalp. Next, gather hair under a kerchief, leave for 20 minutes and after — wash the hair.

If the infection is violent, the scalp is treated by combining the emulsion and shampoo.

  1. On the scalp emulsion is applied, set aside for 30 minutes, covered with a scarf;
  2. thoroughly wash off the emulsion;
  3. is washed twice with a Pedilin shampoo, leaving for 3 minutes each time;
  4. is thoroughly washed;
  5. comb out a thick comb of dead insects from the hair.


  • Shampoo Pedilin is contraindicated in allergies to components of the drug, hypersensitivity.
  • No remedy for children under 2 years of age.

Side effects of

The drug may cause itching, burning, allergic reaction. Long-term exposure to the drug may cause side effects due to excess of the dose. Symptoms of overdose appear:

  • changes in blood pressure — hypertension, hypotension;
  • violation of heart rate — tachycardia, bradycardia;
  • by lacrimation, drooling;
  • visual impairment;
  • excitement;
  • convulsions;
  • by intestinal colic;
  • urinary incontinence;
  • with nausea, vomiting;
  • with cyanotic skin;
  • sharp weakness.

Special instructions

  • Avoid contact with Pedulin shampoo or Pedilin emulsion on mucous membranes. If the product has got into the eyes, mouth cavity, you need to rinse well with cool water.
  • The towel, comb, headscarf, bed linen must also be carefully treated with an insecticide to avoid repeated infection with parasites.
  • Family members should also wash their hair with Pedilin, change bed linen, and treat the comb.
  • No interaction with other drugs.


Reviews of Pedilin shampoos are mostly positive, although opinions are roughly divided 50/50. Negative feedback is associated with inefficiency, a pungent odor.

Possible cause of the lack of effect may be a violation of the recommendations of the instruction:

  • use when expired;
  • absence of simultaneous treatment of the scalp from all members of the family without exception;
  • violation of personal hygiene rules — use of one comb, a common towel, bed linen.


Analogues of Pedilin shampoo include Ceremical water, MediFox, Nix, Pair plus, Permetric ointment, Nittifor, Chigia.

Got lice?

Splitting hairs over which treatments work

John Hoffman March 13, 2007

Your eight-year-old daughter brings home a school letter warning of a lice infestation. A quick scalp check brings the moment you’ve been dreading. You hit the Internet only to find a diversity of opinion on the subject. An Internet search for lice treatments will yield dozens of new remedies, treatments and lice removal tools. Some people and groups are against chemical insecticide-based lice shampoos. Others cite them as the first-line treatment of choice.

Various alternative treatments, such as tea tree oil, enzyme-based lotions, olive oil, mayonnaise, even Vaseline, all have their proponents and detractors. Some say you must clean your house like mad to eliminate lice. Others say that’s a waste of time. Many say get the nits out. Others say nits are largely a cosmetic issue. Even supposedly trustworthy authorities, such as medical and public health professionals, professional nitpickers and medical entomologists, disagree at times. Scratching your head yet? Don’t worry: We’re going to help you pick through this body of conflicting information, issue by issue.

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Some say that insecticide-based lice shampoos don’t work; others say the problem is that people don’t use them properly.
There is some truth in both camps.

The resistance is well documented in several countries, and lots of parents and practitioners report anecdotal evidence. However, that does not mean the pediculicide (lice-killing) products never kill any lice, and it’s possible that improper use is one reason lice shampoos and lotions don’t always work.

Since at best, pediculicides kill only some lice eggs, a second treatment is necessary to get the lice that hatch a few days later. The general advice is to do the second treatment after seven to 10 days. However, Kosta Mumcuoglu, a medical entomologist and researcher at Hebrew University–Hadassah Medical School in Jerusalem, says the second treatment is best done on the 10th day. “Lice eggs can hatch up to 11 days after they are laid,” he says. “That may be why clinical trials where treatments were spaced six to eight days apart generally show poorer results than studies where the interval between treatments is 10 days.”

If you use a lice-killing product, it’s worth following Mumcuoglu’s advice. Beyond that, here are a few don’ts about pediculicide treatment:

• Don’t overexpose your child by using more than the prescribed amount, leaving it on for longer than directed, or treating your child over and over again. Although short-term, low-level exposure to the amounts of permethrin and pyrethroids (the lice-killing chemicals found in most Canadian over-the counter lice shampoos) is generally safe, these are insecticides. It’s sensible to limit children’s exposure to them. Plus, increasing exposure to an agent that doesn’t work well will not make it effective.

• Finally, don’t count on lice shampoo alone to do the job (see nitpicking).

Does tea tree oil really keep lice away?

Don’t count on it.

Anecdotal reports of tea tree oil used as lice repellent have been around for years. However, Ian Burgess of Insect Research & Development Ltd. in the UK, who has studied how lice are affected by various compounds, says tea tree oil does not have any significant repellent effect. “Even if there is some effect, the active ingredients evaporate too quickly — even if the concentration is very high,” he says. “I recall checking children in one school where one of the parents was hawking her aromatherapy treatments and repellents around to prevent infestation. Her own daughter had so much tea tree oil on her hair that you could smell her across the room. That girl also had one of the heaviest infestations in the school!”

However, Burgess says certain compounds in tea tree oil can kill head lice, at least in a lab setting. What is lacking is data on exactly what concentration is necessary, how long it should be left on and so on. Burgess says most tea tree oil shampoos and rinses are too diluted to be effective. Even if parents added lots of the stuff to regular shampoo, it likely wouldn’t work because the amount of shampoo you use on a child is small to begin with, and chemicals in shampoo can reduce the dose of tea tree oil that reaches the louse. And if that weren’t enough, overuse of tea tree oil can irritate the skin. Burgess adds that resistance to tea tree oil is already showing up in some countries where it is used in small amounts in various hair products.

Does drowning lice with olive oil, Vaseline or mayonnaise work?


Many people say you can drown lice by putting vegetable oil, mayonnaise, Vaseline or a “vinaigrette” of olive oil and vinegar on the hair, and covering it with plastic wrap for a few hours (or overnight). It seems plausible but, in terms of proof, all we know is that scientists at the Harvard School of Public Health drowned several lice in a petri dish of olive oil. There is no clinical evidence that it works on human heads.

If so many new products and treatments are scientifically unproven, why are people so convinced that they work?

There are several possible reasons.

For one thing, all experts agree that lice are often misdiagnosed. So it’s possible that some people who used an alternative treatment may have ended up lice-free because they didn’t have live lice or eggs in the first place. Another possibility is that the treatments actually do work some of the time, possibly with low-level infestations. Another is that the substance stunned (but didn’t kill) the lice, making them easier to find, and then the person did a good job removing them with a nit comb. So many variables exist that it’s possible to misinterpret success or failure of any given treatment.

Are there any new mainstream treatments that seem promising and safe?

Some new non-insecticide remedies are being introduced.

Altana Pharma, a drug company based in Oakville, Ont., has introduced Resultz — the first Health Canada-approved lice treatment that is not insecticide based. Used much in the same way as lice shampoos, Resultz is made from ingredients commonly found in cosmetics and dermatological creams. The active ingredient is isopropyl myristate, an emollient that breaks down the wax on the exoskeleton of a louse, causing death by dehydration. One study by an independent testing lab found that 28 of 29 subjects treated with Resultz were lice-free after 21 days. There were some reports of minor skin irritation and redness (as can be the case with pediculicides). Resultz is available in most major Canadian pharmacies and Zellers.

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Other non-insecticide lice products, not yet available in Canada, use dimethicone — another common component of cosmetics — as the active ingredient. One, RID Pure Alternative, is available only in the US. Ian Burgess was involved in the testing of another dimethicone-based product called Hedrin, which is available only in Europe. He says it’s an effective alternative to pediculicides. His study showed a success rate of 70 percent.

Researchers at the University of Utah have developed a device called the LouseBuster, a sort of mini blow dryer that, according to an article in Pediatrics last November, kills lice and nits in a 30-minute treatment by drying them out. The LouseBuster delivers about twice as much air as a conventional hair dryer, though the air is cooler (30 minutes of treatment with a hot blow dryer could cause burns). It is not yet on the market, but when it is, it will have a hefty price tag — they “hope” it will be less than $1,000 US.

Do I really have to do all that washing, vacuuming and storing stuff in the freezer?

Nope, but you can if it makes you feel better.

Lice-treatment advice often includes instructions to vacuum couches, wash clothes and bedding in hot water, chuck hats in the freezer and bag stuffed toys for two weeks to rid your home of lice. But, really, it doesn’t help.

“Lice are very well-adapted to survive on a human head, and not anywhere else,” says Julia Wallace, former parasitologist and lice researcher now in Dwight, Ont. “Even their little claws are adapted to cling to human hair as opposed to any other type of hair or fibre. If lice are off the head, they are most likely dead or dying.”

In the 1980s, Wallace was involved in UBC studies that helped to prove it took two pediculicide treatments to get rid of lice, contrary to what manufacturers were saying at the time. She treated several dozen families with two applications of standard lice shampoos plus removing lice and nits with a lice comb. “We told our families not to do laundry or housecleaning, and we didn’t have a single treatment failure,” Wallace says.

One Australian study, which examined the pillows of subjects with known lice infestations, did find two pillowcases (out of 48) with one live louse nymph each. OK, so wash the bedding. But you’d probably do that anyway.

How important is nitpicking really?


Most lice-treatment instructions include a section on getting out the nits (lice eggs). However, some sources, like the Canadian Paediatric Society, don’t mention it. And at least one prominent expert, Richard Pollack of the Harvard School of Public Health, says nit removal is not necessary. “Because most [head lice] eggs will be non-viable, their removal is often impractical and unjustified,” Pollack states on the school’s website.

Here are four good arguments in favour of nit removal.
• Anecdotal and scientific evidence suggests that you can’t depend on any single lice treatment to do the job.

• Though removing lice and nits by hand (with a comb) requires diligence and a good nit comb, it can be done. And if the lice and nits are gone from your child’s head, she doesn’t have lice anymore. For sure.

• “Nit removal makes it easier to monitor lice outbreaks in schools,” Wallace says. “It’s very hard for volunteers to tell the difference between viable and unviable nits, and live lice can be hard to find, so lice are usually diagnosed based on the presence of nits.”

• Weekly nit combing, even after you are certain that your child is lice-free, is the best way to catch a new infestation at an early stage when it’s easier to deal with.

Those who preach the merits of nit removal say you need a good stainless-steel comb to do the job properly. Dawn Mucci from Innisfil, Ont., who takes nits out of people’s hair for a living, recommends these:

Nit-Free Terminator: “Its teeth have rounded ends so they are easy on the scalp,” says Mucci, “and the tines have little microgrooves that tear the nits and lice as you pull them out.” Available for $23.95, plus shipping and taxes, from Mucci’s website,

The Licemeister: This high-quality nit comb is also on Mucci’s website. “Stainless-steel combs remove the lice and nits more effectively than plastic combs,” Mucci says, “without tearing a child’s hair.”


Apply NYDA in 4 easy steps

1. Spray all over hair

    NYDA should be applied to dry hair Spray the hair roots thoroughly

    Massage in until the hair is completely wet Allow NYDA to work for 30 minutes

After 30 minutes

3. Comb hair carefully with NYDA’s lice comb

    After 30 minutes the dead lice and larvae can be combed out with the NYDA® lice comb. (Make sure you have the right comb) Leave the product on during 8 hours
The NYDA® Lice Com (Included with the NYDA® solution)
The NYDAComb (Sold separately)

If you apply NYDA® in the evening, make sure to put a thick towel on your pillow so that the solution is not absorbed by your bed!

4. Wash with any regular shampoo

Then, wash your hair with your usual shampoo. You can use any regular shampoo that you normally use.

Now your child can return to school!

If necessary the application should be repeated as described above. In any event, the result of treatment should be re-checked after 8-10 days and apply a 2nd time to ensure full eradication of head lice.

APPLICATION CAUTIONS : Because some of the ingredients are inflammable NYDA® must not be used near open fire or incandescent objects. Keep NYDA® away from heat and ignition sources and do not smoke during the treatment.

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The pesticide-free treatment that eliminates lice in 58 seconds

    Eliminates lice from the first application Kills the eggs (nits) and not only lice Effective for all hair types
    Does not contain any pesticide Does not contain any neurotoxic chemicals Safe for hair Suitable for children 2 years and older Has a pleasant smell, appreciated by children

  1. Spray all over hair
  2. Massage
  3. Comb hair carefully
  4. Wash with any regular shampoo

NYDA vs other products

Number of Applications

Adapted from : MSSS. “Intervention guide: Guidelines for controlling head lice in schools and childcare centres”,
[online – https://publications.msss. 000466/ (French only)], 2012.

NYDA is a revolutionary topical treatment

How does it work?

All about lice

Head lice home treatment and remedies

Our grandmothers handed down more than recipes for apple or sugar cream pie. They also passed on myriad so-called miracle home remedies. Made using ingredients readily available [. ] Read more >

Practical tips for a lice-free start to the school year

Practical tips for a lice-free start to the school year As the first week of the new school year dawns before us, children delight in reconnecting [. ] Read more >

Life Cycle of Head Lice & Eggs

The head louse develops in three stages: egg (nit), larvae or nymph (1-2 mm long) and adult. When treating head lice infestations, it is essential to effectively [. ] Read more >

Available in all pharmacies

This product may not be right for you. Always read and follow the label.

The contents of this site are for informational purposes only and are not intended, nor should they be used, as a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician, pharmacist or other qualified health care provider with any questions you may have regarding a medical condition and/or the use of these products. Also read the product monograph and the consumer information included in the product packaging.

58 second s It would already be fixed!

NYDA is a fast and safe treatment against lice. This anti-lice treatment kills lice and nits and is available in all pharmacies across Canada. Ask about NYDA to your pharmacist!


Ask your doctor about Sklice Lotion today

Sklice Lotion is the #1 prescribed brand for head lice in the US with more than 1,000,000 prescriptions filled since 2012 1

10-minute head lice treatment with no nit combing required 2

Eligible parents may pay no more than $30* for their Sklice prescription

Sklice Lotion is approved for use in children 6 months of age and older 2

Patient Brochure also available in Spanish

*Eligible patients may pay no more than $30 for their Sklice prescription. Cash-paying patients will receive a retail discount of $195. Simply present this Sklice Lotion savings coupon to your pharmacist along with your Sklice Lotion prescription. This offer cannot be used if a patient is a beneficiary of, or any part of their prescription is covered by: (1) any federal or state healthcare program (Medicare, Medicaid, etc.), including a state pharmaceutical assistance program, (2) the Medicare Prescription Drug Program (Part D), or if the patient is currently in the coverage gap, or (3) has insurance that is paying the entire cost of the prescription. Any patient may use the cash benefit.

Arbor Pharmaceuticals reserves the right to rescind, revoke, or amend this offer without notice.

See the Sklice Lotion savings coupon for Terms and Conditions.

References: 1. Data on file. Arbor Pharmaceuticals, LLC. 2. Sklice Lotion [package insert]. Atlanta, GA: Arbor Pharmaceuticals, LLC.


To prevent accidental ingestion, adult supervision is required for pediatric application. Avoid contact with eyes.

The most common side effects from Sklice Lotion include eye redness or soreness, eye irritation, dandruff, dry skin, and burning sensation of the skin.

Talk with your doctor if you or your child have any side effect that bothers you or that does not go away. You may report side effects to the FDA at 1-800-FDA-1088 .


To prevent accidental ingestion, adult supervision is required for pediatric application. Avoid contact with eyes.

The most common side effects from Sklice Lotion include eye redness or soreness, eye irritation, dandruff, dry skin, and burning sensation of the skin.

Talk with your doctor if you or your child have any side effect that bothers you or that does not go away. You may report side effects to the FDA at 1-800-FDA-1088 .

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.


Sklice Lotion is a prescription medication for topical use on the hair and scalp only, for treatment of head lice in people 6 months of age and older.


Sklice Lotion should be used in the context of an overall lice management program:

  • Wash (in hot water) or dry-clean all recently worn clothing, hats, used bedding, and towels.
  • Wash personal care items such as combs, brushes, and hair clips in hot water.

A fine-tooth comb or special nit comb may be used to remove dead lice and nits.


  • have any skin conditions or sensitivities
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if Sklice Lotion can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Sklice Lotion passes into your breast milk.

Please see the full Prescribing Information for Sklice Lotion.

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residents only.

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