Permethrin: analogues, instructions for use, price in pharmacies, reviews

Permethrin: analogues, instructions for use, price in pharmacies, reviews

Used for the destruction of lice and other arthropod pests, lotion Permethrin is widely used as an insecticidal drug without pronounced negative manifestations. Features of the composition determine the high degree of effectiveness of this product, which explains the high level of demand for it.

About analogues and prices for the drug, reviews about it and instructions for the use of permethrin, we’ll see today.

Features Permmetrin

Relating to natural pyrethrin, Permethrin contains substances with strong antiparasitic activity. The use of cetylpyridinium bromide increases the insecticidal effect of the preparation.

Composition of

In a 10 ml lotion intended for external use, contains:

  • 60 g of permethrin active substance;
  • additional components: ethyl alcohol, macroglycerine hydroxystearate, purified water, isopropyl alcohol.

In one ml of shampoo, the active substance permethrin contains 10 mg.

About the prices in pharmacies for solutions, ointments, sprays, shampoos, creams Permethrin from lice and other parasites we will tell below.

Dosage Forms

There are three basic forms of this drug available on the market that contains permethrin:

  • solution used for external application,
  • shampoo , available with air conditioner. Shampoo volume 120 ml,
  • aerosol , intended for outdoor use. Vials have a volume of 90 g.

Features of the pharmacological action of

This drug belongs to the species of natural pyrethrinites. They are found in plants that belong to the family of Compositae. Possessing a high degree of insecticidal effect, Permethrin effectively destroys lice and other arthropod pests.

The properties of the drug can be attributed to anti-pediculosis drugs that destroy lice in the scalp and pubic hair. Also causes death of mites, fleas.


Used for the treatment of pediculosis in the diagnosis:

  • pubic lice;
  • pediculosis of the scalp.
  • Permethrin works even when used once for scabies( including nodular, «cleanliness», pseudohetero, Norwegian, typical).And its effect remains even after 3-6 weeks in the treatment of the surface, which was infected with pediculosis.
  • Also, the antituberculous action of Permethrin affects the destruction of parasite eggs.

Instructions for use

General recommendations for the use of the drug are fairly simple. The solution for external use is applied abundantly to the affected area, when applied, the product should be rubbed into the skin. The amount of permethrin used at one time depends on the length of the hair and their density. It can be 10-50 ml of the drug.

After treatment, the head is covered with a kerchief and left for 40-60 minutes. Next, the hair is washed with a large amount of running water at room temperature, using soap or shampoo. To remove dead lice, hair after washing is combed with a frequent comb.

A specific feature of the application should be considered the specific use of the agent in question for various types of disease and their manifestations.

When scabies

Because the product can be used in a variety of forms, its application in garlic varies depending on its consistency.

  • Cream with active substance Permethrin is applied to the affected areas and carefully rubbed with light massaging actions. It should be applied to children and adults, it is desirable completely to the whole body, paying special attention to the scalp. For an adult, usually about 30 g of the drug is sufficient. The remedy is left on the body for 12 hours, then the preparation should be thoroughly washed off with soap. The effectiveness of the drug manifests itself after a single use, but if the itching continues to manifest, the procedure must be repeated after two weeks.
  • In the form of a solution, a 24 ml preparation is used for three days. On the surface of the vial are labels that will allow the product to be better rationed. Permethrin in the form of a solution is used as an aqueous emulsion( concentration 0.4%), which is applied at night and rubbed into the affected area of ​​the trunk, arms and legs. The solution should not be treated with the face, scalp and neck area.

For pediculosis

For the treatment of pediculosis, a 1% cream or a liquid solution is used, as well as Permethrin in the form of a shampoo.

  1. The selected form of the drug is applied to a cotton swab, with which it is rubbed into the hair( their roots).The average person requires about 15-50 ml.
  2. The hair is covered with a kerchief for 40 minutes.
  3. Next, the hair is thoroughly washed with shampoo, and to remove dead lice comb through a frequent comb.
  4. If one-time processing is not enough, then after a week, repeat the processing.

Special cases of

In the treatment of scabies and lice, remember that the use of permethrin should be carried out as carefully as possible in several cases:

  • during pregnancy, , when allergic manifestations may occur in both the pregnant woman and the unborn child;
  • in children under 2 years of age — use this product in a more dilute form to prevent general intoxication of the child’s body;
  • with the sensitivity of to the active substance. In this case, other agents with a similar effect should be chosen to influence lice.
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Malotoxic drug, Permethrin can still cause a number of side effects, which can be avoided with the most careful observation of the patient’s condition during the application of the drug.


Contraindications include cases where the use of this drug causes serious health problems. These include the following situations:

  1. excessive sensitivity to the active substance with the manifestation of allergic reactions;
  2. children’s age( less than two years);
  3. pregnancy;
  4. lactation — if lactation occurs with pediculosis or scabies and requires the use of drugs containing Permethrin, the child should be transferred to artificial feeding;
  5. in the presence of other skin conditions.

Side effects of

Low toxicity causes a small number of side effects in the treatment of scabies and lice using it. To local allergic manifestations in the application of permethrin should be attributed burning and the appearance of mild itching, numbness of the skin, tingling it, as well as puffiness and rashes.

If the listed side effects continue for more than 3 weeks from the date of treatment, you should see an allergist who will prescribe the treatment.

Special instructions

  • Caution should be exercised when using the product, do not allow it to enter all mucous membranes.
  • If the product has got on them, then it is required to wash the mucous membranes with a large amount of warm water.
  • It is better to conduct treatment not indoors, but on the street or with good ventilation.

Interaction with other drugs

If you use Permethrin with other medicines, there is no evidence of an allergy, but if you develop allergic manifestations in the treatment of scabies or lice, using other forms of medication, you should definitely see a doctor.

Below are reviews about the product Permethrin in the form of shampoo, spray from lice, scabies and other parasites.


According to reviews, Permetrin can be attributed to drugs against pediculosis, which is particularly effective and at the same time low in toxicity. The price at the same time the cost of the drug is fairly democratic, and it can be found in many pharmacies.

  • For example, Sergei Ivanovich, 52, comments on Premetin as follows: «The appearance of lice in me was a surprise. But after a single use of Premetrin, burning and itching stopped worrying me, all the insects were gone. An allergic reaction did not occur. I’m happy with the drug. «
  • Elena Alexandrovna, Chelyabinsk, 32, also responds well to the effectiveness of the drug in question: «My son, after staying in the summer camp, was diagnosed with scabies. The doctor appointed Permetrin. After two times the use of the skin has acquired a healthy hue, puffiness has passed, the itching does not bother anymore. «


The following drugs should be classified as having the same effect:

Doctor Komarovsky in this video will tell you how to protect yourself from skin parasites with the help of Permethrin and other means:


Brand Name: Nix, Elimite, Acticin

Generic Name: permethrin

Drug Class: Scabicidal Agents; Pediculicides, Topical

What Is Permethrin and How Does It Work?

Permethrin is used to treat head lice, tiny insects that infest and irritate your scalp. Permethrin is also used to help avoid infestation in people who have close contact with someone who has head lice. It belongs to a class of drugs known as pyrethrins. Permethrin works by paralyzing and killing lice and their eggs (nits).

Permethrin may also be used for pubic lice.

Permethrin is available under the following different brand names: Nix, Elimite, and Acticin.

Dosages of Permethrin:

Dosage Forms and Strengths

Dosage Considerations – Should be Given as Follows:

  • Cream: Apply from head to toe, leave on for 8-14 hours, rinse; may reapply in 7 days if live mites reappear
  • Single application usually curative

Head Lice and Nits (Eggs)

  • Lotion/cream rinse/liquid: apply to washed hair, leave on 10 minutes, rinse and comb out nits and eggs; may repeat in 7 days if lice or nits still present
  • Single application usually curative

Scabies and Head Lice, Pediatric

Children under 2 months

  • Safety and efficacy not established

Children over 2 months

  • Scabies: Apply cream from head to toe; leave on for 8-14 hours, rinse; may reapply in 7 days if live mites reappear; single application usually curative
  • Head Lice and Nits (Eggs): Apply lotion/cream/liquid to washed hair, leave on 10 min, rinse and comb out nits and eggs; may repeat in 7 days if lice or nits still present; single application usually curative


What Are Side Effects Associated with Using Permethrin?

Side effects of permethrin include:

  • Mild and transient burning and stinging
  • Itching
  • Skin redness
  • Skin swelling
  • Skin rash
  • Numbness or tingling where the medicine was applied
  • Scabies symptoms may temporarily worsen after treatment

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Permethrin?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Permethrin has no known severe, serious, moderate, or mild interactions with other drugs.

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

What Are Warnings and Precautions for Permethrin?


  • This medication contains permethrin. Do not take Nix, Elimite, or Acticin if you are allergic to permethrin or any ingredients contained in this drug.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
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  • Hypersensitivity
  • Children less than 2 months of age over-the-counter (OTC)

Effects of Drug Abuse

No information provided.

  • May exacerbate itching, swelling, and redness temporarily.
  • See «What Are Side Effects Associated with Using Permethrin?»
  • See «What Are Side Effects Associated with Using Permethrin?»
  • May exacerbate itching, swelling, and redness temporarily
  • For external use only
  • Avoid contact with eyes
  • May cause difficulty breathing or asthmatic attack in patients with ragweed allergies
  • Permethrin may be acceptable for use during pregnancy
  • Either animal studies show no risk but human studies are not available or animal studies showed minor risks and human studies were done and showed no risk
  • It is not known if permethrin is distributed in breast milk; a physician may temporarily withhold the drug while the mother is nursing


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Brand Names: Acticin, Elimite, Lice Bedding Spray, Nix Complete Lice Treatment, Nix Complete Lice Treatment System, Nix Cream Rinse, Nix Lice Control, RID Home Lice Control Spray for Surfaces

Generic Name: permethrin topical

What is permethrin topical?

Permethrin is an anti-parasite medication.

Permethrin topical (for the skin) is used to treat head lice and scabies.

Permethrin topical may also be used for other purposes not listed in this medication guide.

What are the possible side effects of permethrin topical?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have severe burning, stinging, redness, or swelling after applying permethrin topical.

Common side effects may include:

  • mild burning, stinging, itching or mild rash;
  • numbness or tingling where the medicine was applied;
  • headache, dizziness;
  • fever; or
  • stomach pain, nausea, vomiting, diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about permethrin topical?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.


What should I discuss with my healthcare provider before using permethrin topical?

You should not use this medicine if you are allergic to permethrin or to chrysanthemums.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions.

Permethrin topical is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant.

It is not known whether permethrin topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Permethrin topical should not be used on a child younger than 2 months old.

How should I use permethrin topical?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

You may have a temporary increase in itching, swelling, or redness of treated skin when you first start using permethrin topical.

Do not take by mouth. This medicine is for use only on the skin. Do not apply to open cuts or wounds. If the medicine gets in your eyes or mouth, rinse with water. Use the surface spray only on household surfaces and not on your skin.

You may need to shake the medicine before each use. Follow the directions on the medicine label.

To treat scabies:

  • Clean and dry the skin. Apply a thin layer of this medicine to all body parts from the neck down to the soles of the feet. Rub in completely. Leave the medicine on your skin for 8 to 14 hours, then wash it off completely.
  • When using permethrin topical on an infant, also apply the medicine to the scalp, temples, and forehead. Avoid applying near the eyes, nose, mouth, or genitals.
  • If your condition does not clear up within 14 days, apply permethrin topical again.

To treat head lice:

  • Wash your hair using shampoo only (no conditioner or 2-in-1 shampoo). Rinse thoroughly and towel dry the hair, leaving it damp.
  • Protect your eyes with a towel or washcloth. Apply the medicine to completely saturate all hair, and leave it in for 10 minutes. Then rinse with warm water.
  • You may also use a nit comb to remove lice eggs from the hair. Your hair should be slightly damp while using a nit comb. Work on only one section of hair at a time, combing through 1 to 2-inch strands from the scalp to the ends.
  • Rinse the nit comb often during use. Place removed nits into a sealed plastic bag and throw it into the trash.
  • Check the scalp again daily to make sure all nits have been removed.
  • If you still see lice 7 days after your first treatment, use a second application.

To treat pubic lice (crabs):

  • All sexual partners should be treated.
  • Wash and dry the treatment area. Apply permethrin topical to all pubic hair and any surrounding hairs on the thighs and around the anus (avoid areas inside the rectum or vagina).
  • Leave the medicine on for 10 minutes. Then work into a lather and rinse thoroughly with warm water.
  • You may also use a nit comb to remove lice eggs from pubic hair (hair should be slightly damp).

To prevent reinfection, wash all clothing, hats, bed clothes, bed linens, and towels in hot water and dry in high heat. Dry-clean any non-washable clothing. Soak all hair brushes, combs, and hair accessories in hot water for at least 10 minutes.

Use permethrin surface spray to disinfect non-washable items such as:

  • furniture;
  • mattresses and pillows;
  • stuffed toys;
  • hats, gloves, and scarves;
  • headphones or headbands;
  • the inside of a bike helmet; or
  • seats and carpets inside your car.

Stuffed toys or pillows that cannot be washed should be sealed in air-tight plastic bags for 4 weeks. After removing from the bag, vigorously shake the item outdoors.

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Vacuum all rugs, carpets, and car seats. Then throw away the vacuum cleaner bag.

For the most complete treatment of lice or scabies, you must treat your environment (clothing, bedding, etc) at the same time you treat your hair and/or body.

Store permethrin topical at room temperature away from moisture and heat.

Permethrin Cream

Generic Name: Permethrin Cream (per METH rin)
Brand Name: Acticin, Elimite

Medically reviewed by Last updated on Sep 25, 2019.

Uses of Permethrin Cream:

  • It is used to treat scabies.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Permethrin Cream?

  • If you have an allergy to permethrin, chrysanthemums, or any other part of permethrin cream.
  • If you are allergic to permethrin cream; any part of permethrin cream; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take permethrin cream with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Permethrin Cream?

  • Tell all of your health care providers that you take permethrin cream. This includes your doctors, nurses, pharmacists, and dentists.
  • If permethrin cream is taken by mouth, get medical help or call a poison control center right away.
  • Do not use on a child younger than 2 months of age without first checking with the doctor.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Permethrin Cream) best taken?

Use permethrin cream as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Do not take permethrin cream by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
  • Wash your hands before and after use.
  • Put a thin layer on the skin from the neck to the toes. Put in the skin folds, creases, and spaces between the fingers and toes.
  • Trim fingernails short.
  • Put cream under nails with a toothbrush. Throw away toothbrush after use.
  • Wear light clothing while permethrin cream is on your skin.
  • Do not let your skin touch anyone else’s skin while wearing the cream.
  • After 8 to 14 hours, fully wash cream from skin using warm, soapy water.
  • Wash all bedding, towels, and recently worn clothes in hot water or have them dry cleaned.

What do I do if I miss a dose?

  • Put on a missed dose as soon as you think about it.

See also:

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • A burning or tingling feeling that is not normal.
  • Eye irritation.

What are some other side effects of Permethrin Cream?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Itching. Talk to the doctor about what to do.
  • Irritation where permethrin cream is used.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

See also:

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Permethrin Cream?

  • Store at room temperature. Throw away any part not used after use.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about permethrin cream, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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